treatment of migraine

What is Zavzpret?

Orange County Migraine & Headache Center

Zavzpret is a newly FDA approved nasal spray of Zavegepant, a CGRP receptor antagonist, and is for the acute treatment of migraine with or without aura in adults. It is in the same class as Ubrelvy and Nurtec-both oral CGRP receptor antagonists. The dose is 1 spray of 10 mg in 1 nostril in 24 hours. It may work faster than the oral CGRP receptor antagonists, also known as gepants, since it is delivered nasally. Side-effects include bad taste and nausea. It is expected to be available in pharmacies by July 2023.

 

To make an appointment, please call 949-861-8717.

Is the new oral tablet Qulipta for the prevention of migraine as effective as injectable Aimovig, Ajovy, and Emgality?

Orange County Migraine & Headache Center

Results from clinical trials show high efficacy rates with Qulipta. Qulipta blocks the activity of CGRP as do the injectables. We have many patients who have switched to Qulipta and are doing as well or better than the injectable CGRP mAB’s. To see if Qulipta may be a good option for you, please set up an appointment with one of our providers.

 

To make an appointment, please call 949-861-8717.

Can I take Imitrex and Ubrelvy together for my migraine attacks?

Orange County Migraine & Headache Center

Taking a triptan, like Imitrex, and a gepant, like Ubrelvy, together has not been studied in clinical trials. However, they have different mechanisms of action and are not contraindicated to take together. The combination may work better for some individuals than taking either by itself.

 

To make an appointment, please call 949-861-8717.

My Botox wears off after 10 weeks but my insurance will only let me come in every 12 weeks. What can I do during the 2 weeks that it is wearing off?

Orange County Migraine & Headache Center

There are several options for this 2-week period. One is to come into our office for a nerve block or for a Toradol injection. Another option is to go on a preventive during that 2-week period-an example would be Nurtec every other day. The best strategy is to call our office and set up an appointment to discuss treatment options to lessen your migraine burden during that wearing off period.

 

To make an appointment, please call 949-861-8717.